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Docosahexaenoic acid (DHA)

Docosahexaenoic acid (DHA)

You may have heard of Docosahexaenoic acid (DHA)  – an essential Omega-3 Fatty acid, which is essential for many important functions in the body. This long-chain fatty acid plays a crucial role in the structure and function of cell membranes, especially in the brain and eyes. Your body cannot produce DHA itself, so you have to get it through food. In this article, we'll show you everything you need to know about this fatty acid, the health benefits that come with it and who can benefit from it.

What is DHA?

DHA, known as docosahexaenoic acid, is a essential omega-3 fatty acid made from 22 carbon atoms and six double bonds. This chemical structure makes DHA a crucial component of cell membranes, particularly in brain and retinal cells. By integrating into these membranes, DHA helps maintain cell structure and function, which is essential for your brain and eye health.

One of the special properties of docosahexaenoic acid lies in the position of the first double bond, the omega 3 fatty acids differ from omega-6 fatty acids. This double bond is crucial for the functionality of Omega-3 fatty acids as it influences the structure and flexibility of the fatty acid molecules. Compared to saturated fatty acids, omega-3 fatty acids are more flexible due to their double bond and can be better incorporated into cell membranes. This flexibility contributes to the fluidity of membranes and supports signaling between cells. This also explains some of the health benefits of omega-3 fatty acids, which we will explain to you below.

Natural occurrence of Docosahexaenoic acid

You can find DHA in various foods, especially in fatty fish such as salmon, mackerel, sardines and herring . These fish feed on algae rich in omega-3 fatty acids and store DHA in their fatty tissue. Therefore, they are a great natural source of DHA. Some types of algae contain high amounts of DHA themselves, making them a suitable option for vegetarians and vegans who want to meet their DHA needs.

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Difference between DHA and EPA

 You may be wondering what the difference is between DHA and Eicosapentaenoic acid (EPA) is. Although both are omega-3 fatty acids and offer similar health benefits, there are differences. DHA is particularly important for brain and eye health, while EPA is known for its anti-inflammatory properties and often to support cardiovascular health is used. If you would like to know more about the health benefits of Omega-3 fatty acids , then the best thing to do is read our magazine article.

Forms of DHA absorption

There are various ways to absorb docosahexaenoic acid. A common method is to take food supplements in the form of fish oil capsules or algae oil preparations. These offer a convenient way to get a sufficient amount of DHA, especially if you limit your fish consumption or do not want to consume fish products. Another advantage is that you prevent exposure to heavy metals. Fish often contains high concentrations of substances that are harmful to health, such as mercury. A prominent example of mercury poisoning is the American doctor Dr. Hyman.

Another option is to integrate foods rich in docosahexaenoic acid into your diet. In addition to fatty fish and seaweed products, some other foods such as walnuts and flax seeds also contain lower amounts of omega-3 fatty acids, including DHA. By consuming these foods regularly, you can naturally increase the DHA levels in your body.

What foods contain DHA?

The exact amounts of DHA vary, but here are some foods that are rich in DHA:

  • Salmon
  • Mackerel
  • Sardines
  • Herring
  • Algae (e.g.b Spirulina, Chlorella)
  • Walnuts
  • Flaxseed

Effects and advantages of Docosahexaenoic acid

 DHA has many health benefits. It supports brain development and function, especially during pregnancy and in the early years of life. Studies show that an adequate intake of docosahexaenoic acid the can improve cognitive function, strengthen memory and reduce the risk of neurodegenerative diseases such as Alzheimer's and dementia.

DHA also plays an important role in maintaining vision and retinal health. It is an essential component of the photoreceptors in the eyes and helps prevent age-related macular degeneration and dry eyes.

In addition, DHA has anti-inflammatory properties and can reduce the risk of cardiovascular disease by regulating cholesterol levels, protecting blood vessels and the Inhibits blood clotting.


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The prenatal intake of DHA

If you are pregnant or planning to become pregnant, it is important to pay attention to your diet to support your baby's optimal development. A crucial component is the intake of docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for the development of your baby's brain and eyes.

Why is DHA important during pregnancy?

 DHA plays a crucial role in the development of your baby's central nervous system and retina. During the prenatal period, the supply of DHA is passed on to the developing baby via the placenta. Adequate intake of DHA during pregnancy can therefore help support your child's cognitive development and vision.

How much DHA should you take during pregnancy?

The recommended intake of DHA during pregnancy varies depending on the individual needs and health of the mother. The American Pregnancy Association recommends a daily intake of at least 200 -300 mg DHA during pregnancy.

Current study situation on DHA

Research on the health benefits of Docosahexaenoic acid  is extensive. A meta-analysis of studies found that supplementation may improve cognitive function in older adults. Another study showed that adequate DHA intake during pregnancy can reduce the risk of premature birth.

Further research has shown that docosahexaenoic acid can have a positive effect on mood and emotional well-being, by supports the production of neurotransmitters such as serotonin and dopamine.

DHA and the LDL level

Some studies have found that taking DHA alone or together with EPA can lead to an increase in LDL cholesterol levels, especially in people with certain lipid metabolism disorders. This may be confusing, because after all, a low LDL level is important for the health of our vessels, right?

Well, the answer to this question is not that simple. However, there are reasons why omega-3 fatty acids may cause an increase in LDL cholesterol levels in some studies. On the one hand, the dosage seems to play a role. In some studies, very high doses of up to 6 g per day were administered, which may have contributed to this effect.

Furthermore, omega-3 fatty acids do not appear to increase the amount of LDL cholesterol produced, but rather is more likely to act on the LDL receptor, which means that less LDL can be absorbed from the blood into the cells. This can cause LDL levels in the blood to rise even though the actual production of LDL does not increase.

It is also important to note that these results were primarily observed in people who already had very high triglyceride and LDL cholesterol levels. This suggests that the effect of omega-3 fatty acids on LDL levels depends heavily on individual baseline values ​​and does not necessarily apply to everyone.

Conclusion

Docosahexaenoic acid (DHA) is an important omega-3 fatty acid with numerous health benefits. By consuming DHA-rich foods or using supplements, you can help improve your health and increase your well-being. Regardless of whether you choose fish, algae or other sources, an adequate intake of DHA is crucial for your body to function optimally.

Literature

  • Gutiérrez, Saray et al. “Effects of Omega-3 Fatty Acids on Immune Cells.” International journal of molecular sciences 20,20 5028. 11 Oct. 2019, Link
  • “Omega-3 Fatty Acids and Depression: Scientific Evidence and Biological Mechanisms.” (2014). Link
  • “Office of Dietary Supplements– Omega-3 Fatty Acids.” (2021). Link
  • “Omega-3 Supplements: In Depth.” (2021). Link
  • “Omega-3 acid ethyl esters: EMA confirms omega-3 fatty acid medicines are not effective in preventing further heart and blood vessel problems in patients who have had a heart attack.” (2018). Link
  • “Risk assessment on omega-3 fatty acids.” (2023). Link
  • “Supplements containing omega-3 fatty acids can increase the risk of atrial fibrillation in heart patients.” (2023). Link

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The images were acquired under license from Canva.

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