Collagen is one of the most abundant proteins in our body. It makes up a large part of our connective tissue, which consists of long, fiber-like molecules. Depending on its composition, collagen can have different properties. For example, collagen gives our skin structure and collagen built into the tendons ensures greater tensile strength.
With age, the collagen content decreases more and more. The consequences: Our skin structure becomes brittle and wrinkles, while our tendons are no longer as resilient as they used to be. You can find out here what the background is and how you can partially stop this decline.
Collagen in our body: the structural basis
With a proportion of almost 30%, collagen is by far the most common protein in our body. It is formed by specialized cells called fibroblasts. Three amino acids are strung together until long, fiber-like molecules are formed. It always starts with Glycine.
The long, thread-like molecules are then connected to form a so-called triple helix . Imagine a braid, this is what the collagen structures look like. Finally, these intertwined molecules first assemble in smaller packages to form “fibrils” , which in turn are then formed by the large number of Collagen fibers form.
Did you know? Two important enzymes in collagen synthesis, prolyl hydroxylase and lysyl hydroxylase both require Vitamin C as cofactor. Without enough vitamin C, these enzymes cannot attach the important hydroxyl groups that are later necessary for the cross-links. To put it simply, the resulting collagen would be significantly more unstable.
Low molecular collagen peptides in powder form are a way to prevent the age-related decline in collagen levels.
The framework for healthy and firm skin
The collagen in our skin is constantly being regenerated by the fibroblasts. The large collagen fibers serve as a kind of tight network in which the various other molecules are arranged. Too much UV light and age lead to lower collagen levels over time. The result: Our skin wrinkles. But why is that?
As always, there is no simple answer to a fairly complex question. Researchers are aware of several factors. On the one hand, there is UV radiation, which damages our skin in two ways: Firstly, the activity of the fibroblasts is inhibited, so that less collagen is formed and secondly, more collagen is produced damage to the skin, which activates so-called collagenases. These enzymes actually “digest” functional collagen.
The composition of collagen fibers also changes with age. They become thinner, so that our framework becomes increasingly fragile. The exact cause of this is not yet entirely clear. One hypothesis is that with age, the blood supply, especially through the tiny vessels, deteriorates and collagen formation is therefore impaired.
Interestingly, UV damage appears to be unrelated. This means that here we already have an effective starting point for preventing premature skin aging: Regular application of sunscreen containing UV protection (preferably 50+) can effectively prevent skin aging.
Did you know? In addition to collagen, hyaluronic acid is extremely important for healthy skin and healthy joints. While collagen is insoluble in water and scores above all with its stability and strength, hyaluronic binds extraordinarily large amounts of water and thus provides volume. Nevertheless, the hyaluronic content in our skin decreases with age, which makes it appear less “plump”. Some studies have shown that oral supplementation with high molecular hyaluronic acid can reduce the depth of wrinkles. More about this: What is Hyaluron?
Collagen and hyaluronic acid fight together for more skin elasticity and health as we age.
Less wrinkles thanks to collagen?
It can be observed that lower levels of both hyaluronic acid and collagen lead to more wrinkles as we age. The logical consequence: We have to manage to increase the collagen concentration again. We have already seen one way.
With sufficient sun protection we can effectively protect our skin from harmful UV radiation. This alone is usually only a partial step - ideally we manage to stimulate collagen production. However, we cannot simply apply collagen to our skin. The molecule is far too large and would never get through our skin barrier. Another route is through our gastrointestinal tract, where we can absorb collagen.
Did you know? The amino acid glycine is not only the ultimate for the skin. As a neurotransmitter, the molecule helps regulate nerve impulses and also promotes muscle growth. This amino acid has also sparked interest in aging research.
GlyNAC - the combination of glycine and N-acetyl-cysteine - was able to stop aging in both humans and animals by increasing the production of glutathione - our body's most important free radical scavenger - supports.
Low molecular vs. High molecular weight – a small but subtle difference
As already mentioned, collagen is made up of very long, cord-like molecules. These can be found, for example in some animal products, such as bone marrow, chicken skin or in fish. After absorption, these collagen molecules are broken down by stomach acid and broken down into their amino acids. What initially sounds disadvantageous is actually necessary. The individual amino acids can be absorbed into our body from the intestine - Collagen as a whole would not fit through our intestinal wall.
If you want to supplement collagen, it is preferably already broken down into smaller pieces and additionally packed in a protein shell. Without this “preparation” it seems to have no effect. The studies on humans were carried out either with high-molecular-weight collagen, meaning there were large collagen chains in the protein shells, or with low-molecular-weight collagen. If you look at the studies more closely, low molecular weight collagen shows significantly better results.
The authors of this study also provide an explanation for this. The smaller molecules can be better absorbed by our intestines and thus reach the skin, where collagen synthesis is ultimately stimulated. With larger molecules we have the problem that our intestines cannot fully absorb them and they are broken down instead.
Be careful when choosing the right collagen supplement. According to studies, low-molecular-weight preparations are significantly more efficient.
Collagen as an osteoarthritis killer - what's the point?
In addition to the skin, we find collagen in our joints and the tendons, with which our muscles attach to the bones. Here, too, we see that collagen density decreases with age. Our joints hurt due to arthritic changes, the tendons can no longer carry the load as efficiently as in previous years and we are becoming “stiffer” overall. Collagen can also help here?
To answer this question, we can look at this meta study . A meta-study is a research work that brings together and evaluates as many studies as possible on the same question. In this way you try to eliminate random results and get a little closer to the “truth”.
The researchers found that daily intake of 5-15g of collagen led to improved joint function and less pain. The older the subjects were, the more they benefited from daily collagen intake to increase strength. This effect was smaller in younger, fitter test subjects, but could be increased with the addition of vitamin C.
Citrus fruits are an important natural source of vitamin C - an essential co-factor for the synthesis of collagen.
Here, the researchers found that vitamin C in combination with supplementation of collagen can increase production by the fibroblasts. This makes sense if you can remember the complicated-sounding enzymes of collagen biosynthesis. Two of them require vitamin C as a co-factor.
A final, interesting fact that the scientists bring out in their meta-analysis is the effect of collagen on the recovery time of the muscles after training. Here, a small but measurable improvement was found in the time when the test subjects took collagen.
Did you know? Have you ever heard of brittle bone disease (osteogenesis imperfecta) heard? This rare, genetic disease is caused by a disorder in collagen formation. There are 11 different forms of the disease. Depending on the severity of the disease, the fragility of the bones increases to such an extent that they literally shatter like glass.
Collagen types explained: which type does what?
There are at least 16 different types of collagen, but most scientists focus on the first four main types: collagen types I, II, III, and IV.
- Collagen Type I: This is the most common type and is responsible for the health of skin, hair, nails, organs, bones and connective tissue. It is also the strongest collagen in the body and forms the structure for most tissues.
- Collagen type II: This type is mainly found in the cartilage and plays an important role in building and maintaining healthy joints. It also helps reduce inflammation and relieve joint pain.
- Collagen type III: This collagen is found in large quantities in the skin and blood vessels and helps to keep the skin firm and elastic. It often works hand in hand with Type I.
- Collagen Type IV: This type is essential for skin health and is found in the layers of the skin known as the basement membrane. It supports the functions of skin cells and promotes the formation of new cells.
Vegan collagen alternatives: myth or reality?
Collagen is an essential component of our body, but as an animal product it is not suitable for vegans. However, there are vegan alternatives to promote your body's collagen production.
- Protein: Collagen is made from amino acids, so adequate protein intake is crucial for collagen production. Plant proteins, such as those found in legumes, whole grains and nuts, can help provide needed amino acids.
- Vitamin C: This vitamin plays a key role in collagen formation. It is abundant in many plant foods, including citrus fruits, berries, green leafy vegetables, and peppers.
- Zinc and copper: These minerals are also important for collagen production. They are present in a variety of plant foods, including nuts and seeds, whole grains, and certain vegetables.
- Plant-based collagen boosters: There are also specific supplements that aim to promote collagen production. These often contain a mix of the above nutrients as well as other phytochemicals known to support skin health.
With the Skin Glow Essentials Bundle you combine the power of all three molecules: hyaluronic acid, collagen and glycine for a skin-friendly synergy
Collagen in cosmetics: Is it still current?
Collagen is a popular ingredient in many skin care products and cosmetic treatments, as it is considered an essential building block for healthy skin, hair and nails. But is it really as effective as claimed?
Collagen in skin care products
The idea behind using collagen in skin care products is that it can help tighten skin and reduce wrinkles by supplementing the body's natural collagen production. However, there are some doubts about the effectiveness of these products. According to some experts, the collagen molecules are too large to effectively penetrate the skin and bring about changes at the cellular level.
Collagen in cosmetic treatments
There are various cosmetic treatments aimed at stimulating collagen production. These include Microneedling, laser treatments and ultrasound therapy. A famous user of these methods is the American millionaire Bryan Johnson. These treatments can help rejuvenate skin by stimulating collagen production and improving the appearance of wrinkles and fine lines.
Prevent collagen breakdown – these are options
Collagen is one of our most important structural proteins. However, as we age, the amount of collagen decreases, which leads to wrinkles and weaker tendons and joints. We have various options to prevent this degradation. We can protect our skin from UV radiation and at the same time stimulate collagen biosynthesis by giving our body the building blocks it needs in the form of peptides.
One of the most effective methods for preventing collagen breakdown is a balanced diet. Foods rich in proteins, vitamin C and other antioxidants can promote collagen production. Additionally, certain supplements, such as our MoleQlar Collagen, can help increase collagen levels in the body.
Another important factor in preventing collagen breakdown is Protection against sun damage. UV rays can break down collagen in the skin, leading to premature skin aging. It is therefore important to always use adequate sun protection when outdoors.
Last but not least, regular physical activity can also help prevent collagen breakdown. Exercises that involve the entire body, such as yoga or swimming, can improve blood circulation, helping nutrients move more efficiently to skin cells, which in turn supports collagen production.
The devil is in the details. For collagen, low molecular weight preparations such as MoleQlar Collagen are ideal, while Hyaluron For example, it is significantly more effective in its high molecular form. Together, hyaluronic acid and collagen form an effective duo for your structural health!
