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Inositol

Inositol

What is inositol

Inositol is a sugar alcohol which, like glucose, is an isomer and is an important basic fuel for the cells of the human body. However, unlike glucose, inositol is metabolized differently and does not increase blood sugar levels when ingested with food. There are nine isomers in total, the most important for humans being myo-inositol (MYO) and D-(+)-chiro-inositol (DCI). These inositol isomers all have the same composition but a slightly different spatial structure. It plays an important role in various cellular and biochemical processes, such as signal transduction and hormone secretion.

What is myo-inositol?

Myo-inositol is a biologically active form of inositol and plays an important role in signaling and communication between cells in the human body. Myo-inositol is particularly important in the brain and nervous system.

The role of myo-inositol in insulin resistance

Myo-inositol is a type of inositol that is used as a supplement to combat insulin resistance . This supplement is particularly important for people who suffer from polycystic ovary syndrome (PCOS), as it has been shown to regulate insulin levels. Insulin resistance can be a precursor to diabetes and other metabolic disorders, but there is hope for people who suffer from it. Studies have shown that taking myo-inositol can help normalize insulin balance and reduce the symptoms of insulin resistance. Although further research is needed, it is a promising option for sufferers.

Where is inositol found in the body?

Inositol is a substance that is formed in the body and is found in various organs. Inositol can be detected in the kidneys and liver in particular. However, the highest concentrations are found in the brain, where it plays an important role as an intermediate product in cell metabolism. However, an insufficient or excessive concentration of inositol in the brain can be problematic and can be associated with various diseases such as depression, anxiety disorders, Alzheimer's disease and brain tumors. It is therefore important to keep the inositol concentration in the body in balance to avoid possible negative effects.

Risk of confusion:

Inulin A natural fiber found in foods such as chicory, Jerusalem artichokes and onions. Like other dietary fibres, inulin promotes intestinal activity and can therefore counteract constipation. In addition, this natural fiber is occasionally added to baked goods, dairy products and fruit juices to increase their fiber content. You can find out more about fibre and the role it plays in our intestinal flora in our Microbiome article.

These are the functions of inositol in the human body

Inositol is a versatile substance that fulfills various functions in the human body. As a component of the phospholipids of the cell membrane, it plays an important role in the structure and function of cells. It is also involved in the formation of new cells and participates in the synthesis of lipids. Of particular interest is its function as a precursor in the synthesis of the secondary hormone messengers gonadoliberin, TSH and insulin. It directly influences the hormone balance in the body. It also acts as a secondary messenger in the nervous system and thus influences the activity of neurotransmitters. Overall, inositol is an essential component of our body and therefore plays an important role in human health and well-being.

Inositol can be found in these foods

Inositol is found in many different foods, especially fruits, vegetables, grains and nuts. Some of the foods with particularly high levels of inositol are melons, grapefruits, oatmeal, lentils, beans and soy products.

Inositol as a dietary supplement

Inositol powderis often used as a food supplement to take full advantage of its health-promoting properties. Studies have shown that a higher dosage is necessary to achieve its therapeutic effect. The use of dietary supplements allows for a more precise dosage and higher bioavailability. However, it is important to note that it is also found in foods such as whole grains, nuts and fruits and can be an important part of a balanced diet. The use of inositol as a dietary supplement should always be done in consultation with a doctor or nutritionist.

Conclusion

Inositol is a carbohydrate that occurs naturally in the human body and in many foods. It is involved in numerous biological processes, e.g. signal transduction, insulin processing and calcium signaling. Myo-inositol, a biologically active form, plays an important role in cellular and metabolic functions in the human body. Its potential benefits include improved insulin sensitivity, reduced risk of metabolic disorders such as diabetes and PCOS, improved reproductive and mental health, and improved brain function. Supplementation is a promising therapeutic option for various health conditions.

Literature

https://pubmed.ncbi.nlm.nih.gov/22774396/

https://pubmed.ncbi.nlm.nih.gov/23764390/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140126/

https://pubmed.ncbi.nlm.nih.gov/27717596/

https://pubmed.ncbi.nlm.nih.gov/8293297/

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