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Magnesium oxide

Magnesium oxide

magnesium is an essential mineral for our body, involved in more than 300 biochemical reactions. It is crucial for energy metabolism, the function of heart and muscle cells and for bone health. In nature, magnesium occurs almost exclusively in compounds with various other elements. The range of magnesium supplements is similarly broad. But what makes, for example, magnesium bisglycinate compared to magnesium citrate And why is magnesium oxide preferred in the treatment of constipation, while magnesium sulfate in the Treatment of High Blood Pressure in Pregnancy In this series of articles we will look at the different magnesium compounds and their specific benefits. You can find basic information about magnesium in our introductory article “What is Magnesium?". In this article we focus on the properties and applications of magnesium oxide.

What is magnesium oxide?

Magnesium oxide (MgO), known as magnesia, is an inorganic compound of magnesium and oxygen. Due to its chemical and physical properties, it is widely used in industry, medicine and as a dietary supplement.

It is a white hygroscopic powder with a high melting temperature of about 2,800 °C. In the chemical industry, it is produced by firing magnesium carbonate or magnesium hydroxide, resulting in pure MgO.

Under the Designation E 530, magnesium oxide is used in the food industry as an acid regulator and as a separating agent The reason for this is its chemical properties:

Magnesium oxide as an acid regulator

As an acid regulator, magnesium oxide helps to to control the pH value of food. It reacts with acids and neutralizes them, resulting in the stabilization of pH in an optimal range. This is important for maintaining the taste quality, color and texture of foods, as well as extending shelf life. By regulating acidity, manufacturers can ensure that their products maintain the desired taste and quality over longer periods of time. This is especially important in products that are prone to acidification or where acidity can affect the overall quality of the food.

Magnesium oxide as a release agent

Magnesium oxide is also used as an anti-caking agent to prevent powdered or granular foods from clumping together. It works by absorbing moisture and thereby preventing the formation of clumps. This property makes it particularly useful in Products such as baking powder, salt, sugar, dried milk products and spices, where it helps keep products free-flowing and easy to dose. Magnesium oxide as a release agent improves the handling and quality of food by maintaining the consistency of products and facilitating their processing and packaging.

Natural occurrence

In nature, magnesium oxide is found in the form of the mineral periclaseIt is a component of the Earth's mantle and occurs in metamorphic rocks. Due to its stability, MgO is an essential component in the composition of magnesium-rich rock-forming minerals.

absorption of magnesium oxide

The bioavailability of magnesium oxide is lower compared to other magnesium salts such as magnesium citrate. The body absorbs MgO less efficiently, which must be taken into account when dosing.

Magnesium oxide as a dietary supplement

As a dietary supplement, Mg oxide can be used for various purposes. In this article, we will show you the studies and explain for which purposes magnesium oxide is suitable. For a deeper insight into the functions of magnesium in the body, you can read our What-is-Magnesium Read the article.

Against constipation

Magnesium oxide is effective in treating constipation by acting as osmotic laxative Its mode of action is based on its ability to bind water in the intestine, which leads to an increase in the water content in the stool. This process facilitates bowel movements in several ways:

  1. Water binding: Magnesium oxide draws water from the surrounding tissue into the intestine. This increases the volume of the intestinal contents and stimulates the intestinal walls, which leads to a natural stimulation of intestinal activity.
  2. Softening of the stool: By increasing the water content in the stool, it becomes softer and therefore easier to pass. Softer stools can relieve the symptoms of constipation and make it easier to pass.
  3. Stimulation of intestinal motility: The increased intestinal contents caused by the additional water expand the intestinal walls and thereby stimulate peristalsis, the wave-like movements of the intestine that move stool through the digestive tract.

Magnesium oxide is often used in higher doses as a laxative, as it may not have the same osmotic effect in lower doses. It is particularly useful for people seeking quick relief from constipation, as the effects usually occur within a few hours to a day of ingestion.

Magnesium oxide against heartburn

Magnesium oxide works against heartburn by acting as Antacid acts, which the excess stomach acid neutralized and thus relieves the symptoms of heartburn and stomach discomfort. Heartburn occurs when stomach acid enters the esophagus, causing a burning sensation behind the breastbone. Here are the key aspects of how magnesium oxide helps treat heartburn:

neutralization of stomach acid

  • Magnesium oxide reacts with hydrochloric acid (HCl) in the stomachto form magnesium chloride (MgCl2) and water (H2O). This reaction reduces acidity in the stomach and increases the pH, reducing the burning and irritation caused by the acid.

Fast relief

  • As an antacid, magnesium oxide provides rapid relief from heartburn. The effect often occurs within minutes of ingestion because the powder or tablet dissolves quickly in the stomach and reacts with stomach acid.

Advantages over other antacids

  • Compared to other antacids, magnesium oxide has the added benefit of providing magnesium, an essential mineral that many people do not get enough of in their diet. However, caution should be exercised when using magnesium oxide as an antacid, especially with long-term use, as it may lead to increased magnesium absorption, which could have side effects.

Did you know?

Proton pump inhibitors (PPIs) are the drug of choice for reflux disease, i.e. heartburn. They inhibit the cells in the stomach that are responsible for acid production. In some studies It has been shown that people taking PPIs are more likely lower magnesium levels However, the exact mechanism is not yet understood, since these patients also excrete little magnesium via the kidneys.

In the Everyday Essentials Bundle you will find three products for the most common deficiencies in humans. These include vitamin D, omega 3 and magnesium.

Magnesium oxide for migraines

Some studies suggest that the Supplementation with magnesium oxide can prevent migraine attacksMagnesium plays a role in regulating neurotransmitters and dilating blood vessels, which can reduce the frequency and severity of migraine attacks. In a study became Magnesium oxide compared with the drug valproateFor this purpose, 63 patients were treated for 8 weeks with daily 500mg magnesium oxide The result: Magnesium oxide was similarly effective in migraine prophylaxis as valproate, without significant side effects.

In addition to magnesium oxide, magnesium citrate as helpful in migraine prophylaxis.

forms of magnesium oxide

Magnesium oxide is available in several forms, including capsules and powder. The choice of form depends on individual preference and specific health goals.

Magnesium oxide vs. magnesium citrate

While magnesium oxide has a lower bioavailability, it is cheaper to produce than magnesium citrate. Magnesium citrate offers higher bioavailability, making it a preferred choice for quickly correcting magnesium deficiency. Additionally, magnesium citrate can help against kidney stones.

Side effects of magnesium oxide

Taking magnesium oxide can cause side effects such as gastrointestinal discomfort, nausea and diarrhea. These effects are more common at high doses.

overdose of magnesium oxide

An overdose of magnesium oxide can lead to hypermagnesemia, especially in people with impaired renal function. Symptoms of an overdose can include a drop in blood pressure, difficulty breathing and cardiac arrhythmias. If you want to know more about the topic, then read the article magnesium overdose through.

Conclusion

Magnesium oxide is an important source of magnesium and offers valuable health benefits despite its lower bioavailability compared to other compounds such as magnesium citrateMagnesium oxide appears to be particularly effective in the treatment of constipation and heartburnWhen choosing a magnesium supplement, the individual absorption rate, possible side effects and the purity of the molecules should be taken into account.

Literature

  • Mori, Hideki et al. “Magnesium Oxide in Constipation.” Nutrients vol. 13,2 421. 28 Jan. 2021, Link
  • Lindberg, J S et al. “Magnesium bioavailability from magnesium citrate and magnesium oxide.” Journal of the American College of Nutrition vol. 9,1 (1990): 48-55. Link
  • Khani, Samira et al. “Comparative study of magnesium, sodium valproate, and concurrent magnesium-sodium valproate therapy in the prevention of migraine headaches: a randomized controlled double-blind trial.” The journal of headache and pain vol. 22,1 21. 7 Apr. 2021, Link
  • Gommers, Lisanne M M et al. “Mechanisms of proton pump inhibitor-induced hypomagnesemia.” Acta physiologica (Oxford, England) vol. 235,4 (2022): e13846. Link
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