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What is coenzyme Q10?

What is coenzyme Q10?

Have you ever wondered what actually powers your cells? The answer includes: Coenzyme Q10, also known as ubiquinone/ubiquinol. This molecule is an important component of your body and is considered key to energy and performance.

Ubiquinone is found in almost all biological membranes and plays a role in the Mitochondria – the "powerhouses" of the cells – ensure that your body is supplied with energy. But that's only half the story: It also plays a role in defending against oxidative damage. stress and helps to produce antioxidants such as Vitamin C, Vitamin E and to regenerate glutathione.

However, with age or during times of increased oxidative stress, such as during illness or stressful situations, The natural production of ubiquinone can decrease significantly.This gap in supply can directly affect our mental and physical performance. It's no wonder, then, that coenzyme Q10, in its oxidized form called ubiquinone, has been and continues to be the subject of extensive scientific research in this context.

A system adequately supplied with coenzyme Q10 is important for the immune system, stabilizes cell membranes and provides the basis for optimal cellular performance. – and all of this makes it a central component of a balanced lifestyle for a vibrant life.

How is our body supplied with coenzyme Q10?

Unfortunately, the body's own production is often insufficient – ​​especially from the age of 25, when natural synthesis declines rapidly. Chronic stress, environmental pollution, and certain medications further exacerbate this deficiency. Therefore many foods contain only small amounts of ubiquinoneTargeted and needs-based supplementation can help support energy levels and antioxidant defenses. For this reason, ubiquinone is often considered one of the key nutrients in the longevity field.

Studies show that Ubiquinone plays a role particularly in mitochondrial function. – a crucial factor in post-viral stress or chronic fatigue, which are often associated with reduced energy production and increased oxidative stress.

Currently, intensive research is being conducted on the effect of coenzyme Q10 and its potential in mitochondrial dysfunction - a Hallmark of Aging Research has been conducted. This is characterized by neurodegenerative processes, chronic fatigue, and certain metabolic disorders. This versatility makes ubiquinone a molecule that It could be a factor both in preventive settings and as supportive therapy.Future studies will show in which direction the areas of application will develop.

Occurrence of coenzyme Q10

Coenzyme Q10 is found both in your body and in your food. Here are some of the best sources:

  • Animal sources: Meat, especially offal such as liver, heart, and kidneys, contains particularly high concentrations of ubiquinone.
  • Fish: Mackerel, sardines and herring are rich in ubiquinone and represent an important source for people who consume little meat.
  • Plant sources: Nuts (e.g.peanuts), seeds and vegetable oils such as soybean and rapeseed oil.
  • Vegetables: Spinach, broccoli and cauliflower are also noteworthy plant-based sources, although the concentration is lower than in animal products.

In the human body, the highest concentrations are found in tissues with high energy demands, such as the heart, liver, and kidneys.These organs require ubiquinone to maintain their optimal functions.

Although these foods contain ubiquinone, the amounts are often insufficient to meet the body's needs during periods of oxidative stress or increased demands. Furthermore, Q10 levels decline with age, as is the case with many micronutrients.

What does coenzyme Q10 do?

Energy production

Imagine your cells are tiny high-tech factories, tirelessly producing energy. And this is precisely where coenzyme Q10 plays such a crucial role: It acts as indispensable engine in the electron transport chain of your mitochondria. In this "energy factory", ATP (adenosine triphosphate) is produced – the fuel that powers every single cell in your body.

Organs like the heart and muscles, which have enormous energy demands, are particularly dependent on sufficient levels of coenzyme Q10. Without this molecule, energy production falters – you feel exhausted and lethargic.

Antioxidant effect

Excess free radicals pose one of the greatest challenges to your cells. These unstable molecules attack cell structures and accelerate degenerative processes, thus speeding up the aging process. This is where coenzyme Q10 comes in: As a molecule with antioxidant properties, it protects cell membranes and mitochondria from oxidative stress..

It neutralizes free radicals, thus preventing damage to lipids, proteins, and DNA. But that's not all: Coenzyme Q10 helps regenerate other antioxidants like vitamins C and E, so they can continue to perform their functions in the body. Q10 is therefore a true bodyguard for your cells.

Cellular repair mechanisms

Your cells are under immense pressure every day. Environmental factors, stress, and aging can damage them and impair their function. Coenzyme Q10 supports the repair of these cells by mediating oxidative stress and maintaining energy supply, as mentioned above. It plays a key role, especially in tissues with a high cell turnover rate, such as your skin. It ensures that cells regenerate and function optimally – even under demanding conditions.

Effects of a deficiency

A problem with mitochondrial energy production can affect many areas of your body and cause various symptoms:

  • Decline in performance and exhaustion: These can range up to chronic fatigue syndrome or burnout syndrome.
  • Cardiovascular diseases: Studies have shown a correlation between heart muscle weakness and heart failure with low Q10 levels.
  • Neurodegenerative diseases: Diseases such as Alzheimer's and Parkinson's are associated with problems in mitochondrial function.
  • Diabetes and metabolic disorders: If mitochondria are disrupted, this can lead to... Insulin sensitivity impair and increase the risk of derailment Blood sugar levels increase.
  • immune system: A weakened immune system can increase susceptibility to infections.

Mitochondrial dysfunction It affects ATP production and contributes to symptoms such as fatigue, muscle pain, and declining cognitive performance.In the long term, these symptoms can significantly impair quality of life. Therefore, an adequate supply of micronutrients such as Q10 is essential for maintaining physical and mental health.

Studies have investigated the extent to which supplementation can compensate for a deficiency. It was shown that ubiquinone can have particularly positive effects in cases of chronic mitochondrial dysfunction by stabilizing cellular energy production and reducing oxidative stress.

Different forms of coenzyme Q10: ubiquinol vs. ubiquinone

Ubiquinone exists in two main forms:

  1. Ubiquinone (oxidized form): This form is widespread in its original structure and is converted in the body to ubiquinol when needed to exert its antioxidant properties. In many cases, this conversion process works efficiently, making ubiquinone a generally bioavailable option.

  2. Ubiquinol (reduced form): This form unfolds its antioxidant properties immediately and is often recommended for people who are affected by increased oxidative stress levels or whose conversion processes may be impaired.

Bioavailability

Coenzyme Q10 is a fat-soluble molecule, which is typically associated with poor bioavailability. However, in the case of ubiquinone, the manufacturer of Q10Vital® has succeeded in refining the molecule using a special technology, making it water-soluble. This innovation demonstrably leads to increased bioavailability of the active ingredient. In a comparative study with conventional ubiquinol, Q10Vital® even showed better bioavailability.*

Both forms can be converted into each other in the body and play an essential role in energy metabolism. The choice of the appropriate variant should be tailored to individual needs and health goals. Thanks to modern developments, Q10Vital® Ubiquinone now represents an effective and highly bioavailable option.

Science and research on coenzyme Q10

cardiovascular system

Did you know that coenzyme Q10 also plays a role in changes to the heart muscle? Current research shows that it can not only improve function in cases of pre-existing weakness, but also reduce oxidative stress – a major factor in many age-related changes in the cardiovascular system.Furthermore, a meta-analysis has shown that CoQ10 supplementation can lead to a reduction in systolic blood pressure. In addition, another experimental study demonstrated positive effects on the resilience of the heart muscle.

Brain and nervous system

The role of coenzyme Q10 in brain health is worth a closer look. Research suggests it may protect nerve cells from oxidative stress and improve mitochondrial function. This could be interesting in relation to processes that develop based on mitochondrial dysfunction. Also of interest: it is suspected of helping to maintain cognitive function for longer.

Chronic diseases

Chronic diseases such as diabetes or migraines are also linked to mitochondrial problems. Coenzyme Q10 stabilizes cellular energy production and could therefore have a positive influence on... Inflammation have, which play a central role in this process. In migraine patients, the frequency and intensity of attacks could be significantly reduced through regular intake of coenzyme Q10. Similarly, improved insulin sensitivity and a reduction in oxidative markers are considered effects of a well-functioning supply.

Regeneration after viral diseases

After a viral infection, many people feel exhausted and lack energy. Studies Studies show that supporting mitochondrial function can alleviate symptoms such as fatigue or muscle weakness. This is particularly relevant in post-viral syndromes, where energy production is often severely impaired.

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Literatur:

  • Al Saadi T, et al. (2021). Coenzyme Q10 for heart failure. Cochrane Database Syst Rev. 
  • Díaz-Casado ME, et al. The Paradox of Coenzyme Q10 in Aging. Nutrients.
  • Florou, P. et al. (2020). Does coenzyme Q 10 supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta-analysis of randomized-controlled trials. Journal of assisted reproduction and genetics.
  • Gaul, C. et al. (2015). Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial. The journal of headache and pain.
  • Gröber, U. et al. (2022). Kardioprotektive und pleiotrope Effekte von Coenzym Q10. Zeitschrift für Orthomolekulare Medizin.
  • Kramer, M. et al. (2024). Genetik der oxidativen Stressbelastung der Mitochondrien. Zeitschrift für Orthomolekulare Medizin.
  • Mantle, D. et al. (2024). Mitochondrial dysfunction and coenzyme Q10 supplementation in post-viral fatigue syndrome: an overview. International Journal of Molecular Sciences.
  • Mantle, D. et al. (2019). Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview. Antioxidants.
  • Pravst I. et al. Comparative Bioavailability of Different Coenzyme Q10 Formulations in Healthy Elderly Individuals. Nutrients.
    *nicht signifikant

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